Determinate the BPA in Biological Samples by Spectrophotometry

Boron neutron capture therapy (BNCT) is a new radiation therapy, of which clinical interest has focused primarily on the treatment of high-grade gliomas.At present, the most effective drug for BNCT is p-Boronophenylalanine（BPA), becouse it has little side effect and low toxicity, persisted longer in tumors compared with related molecules. The method of 3-Methoxy-Methylenimine H spectrophotometry was established to measure the concentration of ¹⁰B in biological samples. The biodistribution of the BPA was studied in normal mice.