Development of ⁹⁹Tc^m Labelled Mixed-Ligand Complexes

Recently, mixed-ligand technetium complexes are the novel tracers in nuclear medicine. Some 99Tcm complexes with different ligands were viewed，which include “3+1”,”4+1”,”3+1+1”,”4+1+1”and “2+2”, and their chemical properties, biodistribution and their limits were also discussed. Amone these ligands,the type “2+2” has the best characteristic of chemical and biology, and shows potential application values.