Study on Method of Extraction for Labeling Ytrrium－90 in Lipiodol

Lipoidol plays an important role in curing liver cancer, because it can prolonged selective retain in hepatoma cells. In order to improve labeling efficiency of nuclide yttrium-90 in lipiodol, a new method of extraction is used to label steady yttrium, Di(2-ethylhexyl) orthophosphoric acid (P204)，Di(2-ethylhexyl)phos acid (P507)，Cyanex 272，nonanoic acid，naphthenic acid，oleic acid and 8-oxine are selected as extractants. The results indicate that the labeling efficiency with P204 can reach 99.9%，and that with P507 or Cyanex 272 is also high, but the labeling efficiency is very low with any other extractant. By this method the stability of labeled yttrium-90 with P204 is very good in physiological brine, while the loss efficiency is only 0.01%~0.14%. The extraction method for labeled yttrium-90 has some merits, such as simple operation, brief labeling flow and easy control. Therefore, the method for labeled yttrium-90 with P204 in lipiodol is potential in curing liver cancer.