The Adsorption of ~(188)Re-HEDTMP on Hydroxyapatite

A new alkylphosphine ligand HEDTMP is synthesized and a promisingly radiotherapeutic complex 188ReHEDTMP is prepared. The adsorption characteristics of the complex on HA are investigated. It's found that time, amount of HEDTMP and pH have remarkable influences, while temperature has little influence on the adsorption of 188ReHEDTMP on HA, and the best adsorption condition is shown to be t=10 min, n(HEDTMP)∶n(Re)=50∶1 with pH=1.5. The adsorption stability of 188ReHEDTMP on HA is good.