The Imaging of ~(99)Tc~m-HYNIC-TOC in Pancreatic Tumor Borne Nude Mice

The distribution of 99TcmHYNICTOC in mice and its imaging features in the SSRpositive pancreatic tumor borne in nude mice are investigated in detail. The results show that the blood radioactivity decreased rapidly and the tracer excretes mostly from the urinary tract after injection. SSRpositive pancreatic tumor borne in nude mice can be imaged 1 hour after injection and the image becomes optimal 3 hours later. The clear image indicates that the 99TcmHYNICTOC prepared in this experiment a very promising SSR tracer.