~(90)Y-labeled Monoclonal Antibodies and Peotide-receptor for Tumor Radiotherapy
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Abstract
90Y is a useful radionuclide for radiotherapy due to its energetic β- ray(Emax=2.3 MeV)and favorable halflife(T1/2=64 h) and it can be obtained from 90Sr90Y generator for the carrierfree form. The radiolabeling methods, toxicity and dose estimation in animal and clinical application for the cancer treatment with 90Y labeled monoclonal antibodies and peptidereceptor are summarized.
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