Application of Hydrazino Nicotinamide Derivative in the Radioparmaceuticals Labeling

The hydrazino nicotinamide derivative as an effective bifunctional chelator is widely used to label human polyclonal IgG, chemotactic peptide and DNA oligonucleotides with 99 Tc m. So many potentially useful radiopharmaceuticals may be produced via the hydrazino nicotinamide derivative method. The hydrazino nicotinamide derivative synthesis and use in the radioparmaceuticals labeling are concisely introduced.