Synthesis and Iodine Labelling of β-CIT as a Dopamine Transporter Imaging Agent[J]. Journal of Isotopes, 2000, 13(1): 7-7. DOI: 10.7538/tws.2000.13.01.0007
Citation: Synthesis and Iodine Labelling of β-CIT as a Dopamine Transporter Imaging Agent[J]. Journal of Isotopes, 2000, 13(1): 7-7. DOI: 10.7538/tws.2000.13.01.0007

Synthesis and Iodine Labelling of β-CIT as a Dopamine Transporter Imaging Agent

  • carbomethoxy 3β (4′ iodophenyl)tropane(β CIT) and it's iodine labelling precursor 2β carbomethoxy 3 β(4′ tribuylstannylphenyl)tropane are synthesized, and the chemical structures are confirmed by IR, NMR, MS and elemental analysis. The radiochemical purity of 125 I β CIT and 131 I β CIT are over 90% evaluated by HPLC and TLC.
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