Abstract: Extreme rainfall events occur frequently under the background of global climate changes. As an important contributor to extreme rainfall, typhoons exert significant impacts on regional environment and social economy. Xishuangbanna, located in the southernmost tropical region of Yunnan province, serves as the terminal affected area of westward-moving typhoons. Investigating precipitation δ²H and δ¹⁸O in this region can provide a scientific basis for deciphering the water vapor transport pathway and controlling mechanism of typhoons in tropical China. In this study, rainfall samples were collected before, during, and after multiple typhoon events in Xishuangbanna from 2021 to 2024. Combined with the HYSPLIT backward trajectory model and meteorological data, the temporal variations and dominant controlling factors of δ²H and δ¹⁸O in precipitation were analyzed. The results show that the δ²H and δ¹⁸O in typhoon-related rainfall exhibited a distinct three-stage variation pattern with a unique delayed depletion feature, which usually occured 1-3 days after the typhoon. The depletion magnitude of δ²H and δ¹⁸O in rainfall was mainly controlled by typhoon intensity and the distance between the typhoon low-pressure center and the study region. The correlations between precipitation isotopes and local meteorological factors were more weak with the increasing typhoon intensity, and the influences of local meteorological factors were completely masked during the super typhoons. This study filled the research gap of δ²H and δ¹⁸O in typhoon-related rainfall in Xishuangbanna, and provided implications for understanding the disturbance of typhoons on inland water cycle processes and optimizing regional water resource management.