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用于短寿命同位素生产的10 MeV超紧凑型回旋加速器研制

Development of a 10 MeV Ultra-Compact Cyclotron for Short-Lived Isotope Production

    摘要
  • 摘要: 为应对我国医用回旋加速器严重依赖进口的现状，中国原子能科学研究院自主研制出10 MeV超紧凑型回旋加速器。该装置采用浅谷区磁铁、高频-真空一体化、单次轴向垫补及内部潘宁离子源等关键技术，整机尺寸小于1.4 m3，总重小于7.5 t，具备高集成度与智能化运维特点。在质子能量10 MeV、束流80 μA条件下，连续稳定运行2 h生产的18F产额超过3 Ci，单次可满足15人次临床需求。实验结果表明，该加速器性能可靠、操作便捷，适用于医院现场制备18F、68Ga等多种短寿命同位素。

     

    Abstract: To address the heavy reliance on imported medical cyclotrons in China, the China Institute of Atomic Energy has independently developed a 10 MeV ultra-compact cyclotron, aiming at achieving localized and low-cost production of medical radioisotopes. The device incorporates key technologies including shallow-valley magnets, an integrated high-frequency and vacuum system, single-pass axial shimming, and an internal Penning ion source. It has a compact footprint of less than 1.4 m3 and a total weight under 7.5 tons, and is designed for high integration and intelligent operation and maintenance. Under working conditions of 10 MeV proton energy with 80 μA beam current, the cyclotron maintained stable operation for 2 h, yielding 18F with an activity of over 3 Ci. This output is sufficient for approximately 15 patient doses, fulfilling the clinical demand. The results demonstrate that this accelerator is reliable, user-friendly, and suitable for in-hospital production of short-lived medical radioisotopes such as 18F and 68Ga.

     

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