基于cosRMC的BNCT剂量计算功能开发

Development of BNCT Dose Calculation Function Based on cosRMC

  • 摘要: 为了确保硼中子俘获治疗(boron neutron capture therapy,BNCT)治疗的有效性和安全性,精确的剂量计算和治疗计划至关重要,本研究选取国产自主化蒙特卡罗粒子输运程序cosRMC进行剂量计算,实现医学CT图像与cosRMC输入文件的自动建模转化。选取公开数据集头部CT算例,经CT图像处理、cosRMC建模、中子输运计算、剂量计算等,将计算结果与OpenMC程序结果进行对比。结果表明,cosRMC和OpenMC的平均剂量误差小于3%,初步证明cosRMC可作为BNCT-TPS中剂量计算工具。

     

    Abstract: To ensure the effectiveness and safety of boron neutron capture therapy (BNCT), precise dose calculation and treatment planning are of critical importance. In this study, the domestic and independent Monte Carlo particle transport code cosRMC was selected for dose calculation, and an automatic modeling and conversion process was developed to transform medical CT images into cosRMC input files. A publicly available head CT dataset was chosen as a case study. Through processes such as CT image processing, cosRMC modeling, neutron transport calculation, and dose calculation, the results were compared with those obtained from the OpenMC code. The findings indicated that the average dose error between cosRMC and OpenMC was less than 3%, preliminarily demonstrating that cosRMC can be used as a dose calculation tool in BNCT-TPS.

     

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