<sup>18</sup>F-FDG和<sup>18</sup>F-NaF示踪剂在大鼠经脉的microPET显像

¹⁸F-FDG和¹⁸F-NaF示踪剂在大鼠经脉的microPET显像

摘要: 探讨利用微型正电子发射断层显像（micro positron emission tomography system, microPET)显示示踪剂在足三里穴位注射后沿经脉走行的循经迁移线。分别将0.03~0.1 mL 200~300 uCi的¹⁸F-氟化钠和¹⁸F-FDG注入大鼠足三里穴位，分别进行microPET图像和CT图像采集，将microPET图像和CT图像融合并重建融合后的三维图像。结果表明：¹⁸F-FDG与¹⁸F氟化钠均能显示循经迁移线，但¹⁸F-氟化钠的骨骼摄取明显，¹⁸F-FDG优于¹⁸F-氟化钠在经脉中的显像，表明¹⁸F-FDG更适合用于经脉显像。

Abstract: In order to research the migration line after injection of the tracer to Zusanli acupoint. ¹⁸F-FDG or ¹⁸F-sodium fluoride was injected into Zusanli acupoint of the rats in doses of 0.03~0.1 mL (200~300 uCi). The microPET image and CT image were acquired respectively and fused together and reconstruction of 3D. ¹⁸F-FDG and ¹⁸F-sodium fluoride could show the migration line in meridian objectively, however, the ¹⁸F-sodium fluoride showed significant bone uptake. ¹⁸F-FDG was superior to ¹⁸F-sodium fluoride in meridians imaging. The results showed that ¹⁸F-FDG was more suitable for use in meridians imaging.