Abstract: This article is a review and prospect of the research, development and industrialization of Cobalt-60 digital radiography inspection technology based on the national requirements in the recent 20 years, which is leaded by Institute of Nuclear and New Energy Technology (INET) of TsinghuaUniversity. The research purpose, innovative approach and main academic achievements of this technology were described systematically. The industrial equipment varieties, performance, running condition and application effect were introduced, and the outstanding advantages and prospects of the technology are summarized. In the paper, some understanding obstacles or mistakes encountered during the promotion and application were sorted out and explained too to help the improvement and development of the new relevant technology.