氧-18水批量回收纯化处理工艺

Batch Recycle Purification Technological Process of ¹⁸O-H₂O Wate

摘要: 建立了一套¹⁸O-H₂O回收水批量回收纯化处理工艺。该工艺对¹⁸O-H₂O回收水中的杂质进行了分析，通过紫外杀菌，无菌滤膜过滤除去了菌类和细菌内毒素，通过三次低温蒸馏或C-18柱-二次低温蒸馏除去了可溶性无机和有机杂质，同时保证了同位素丰度符合要求，使¹⁸O-H₂O各项指标达到了加速器药物生产要求，并可达到较高的打靶和合成效率。该工艺的建立可以充分利用一次打靶后的¹⁸O-H₂O回收水，大幅度降低了成本，资源利用更加合理，高效。

Abstract: A batch purification technological process for ¹⁸O-H₂O recycled water is established. The impurities was analyzed firstly. The bacteria and endotoxin in ¹⁸O-H₂O recycled water could be removed by ultraviolet sterilize rand sterile membrane, and soluble impurities removed by multiple cryogenic distillation. This process makes indicators meet the accelerator pharmaceutical production requirements, together with high target and synthesis efficiency. This process, which takes advantages of ¹⁸O-H₂O recycled water produced by accelerator, reduces the cost significantly and utilizes the resources reasonably and efficiently.