Abstract: The researches and the applications on radioisotope technology have been strived for in our Institute (INPC, institute of nuclear physics and chemistry) about 30 years since 80s’ last century. In this paper, the main progress on radioisotope technologies, including radioisotopes produced, radiopharmaceuticals developed, radioactive sources involved, as well as decay energy application were summarized, and presented several considerations in the future based on the radioisotope production line will have been built in INPC recently. This paper was remembered for the centennial of academiciam Xiao Lun birth.