Abstract: A system of capsule automatic dividing for radioisotope solution was developed. In the system the step motors, highly precise wriggle-pumps and other hardware as working-unit were controlled by computer-based platform and all the operational information and data were also processed. A real-time-detect method for the radioactivity has been presented by which the radioisotope automatic precise dividing was realized. The problem of radioactive irradiation has also been solved.This device has been applied and the expected results were achieved.