单纯性肥胖症少儿内分泌功能相关指标的RIA检测

The Analysis of Relative Marks of Endocrine Function in Children With Simple Obesity

摘要: 采用放射免疫分析法(RIA)检测了65例8～12岁单纯性肥胖症少儿和60例正常少儿空腹血糖、总胆固醇、甘油三脂、血清垂体生长激素、血清总T3、T4、TSH,胰岛素、C肽和胰高糖素的含量,结果表明:与对照组相比,肥胖少儿的甘油三脂、胰岛素含量明显增高(P<0.01),生长激素明显降低(P<0.01);空腹血糖、总胆固醇、T3、T4、TSH、胰岛素、C肽均正常。这说明肥胖少儿呈高脂血症且与胰岛素增高、生长激素低下相关。

Abstract: To explore the endocrine function in children with simple obesity,the plasma concentration of BS?TC?TG?GH?TSH?T3?T4?INS?CP?GR are detected by RIA in 65 children with simple obesity and 60 normalweighted children of 8~16 years old. The results show the plasma level of TG?INS increased significantly(P<0.01), and the plasma level of GH decreased significantly (P<0.01),compared with the control group. It suggests that obesity may interfere in endocrine function, obesity may be responsible for the earlier gonadal development and maturity.