HPLC法分析~(18)F-FDG放化纯度
Analysis of the Radiochemical Purity of ~(18)F-FDG by HPLC
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摘要: 采用 8 5 %的乙腈作流动相, 高效糖柱作分离柱, HPL C法分析 18F- FDG的放化纯度。在该条件下, 18F-的参考保留时间为 6.5 0 min,18F- FDG为 9.0 0 min。与同一样品的 TL C分析比较, HPL C分析 18F- FDG时间短、灵敏度高。因此采用 HPL C分析 18F- FDG的放化纯度优于 TL CAbstract: The radiochemical purity(RCP) of 18 F FDG is analyzed by HPLC. Eighty five percent acetonitrile is used as the eluting solution. Carbonhydrate column is used as separation column. The t R of 18 F - is 6.50 min and 18 F FDG is 9.00 min. HPLC take less time and has higher sensitivity than TLC for the same sample at the same time. So HPLC excells TLC in analyzing RCP of 18 F FDG.
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