Abstract: The preparation of Pt SDB hydrophobic catalyst is studied, in which platinum as active metal and polystyrene divinylbenzene(SDB) as the carrier. Hydrogen isotope exchange reaction is carried out with Pt SDB catalyst in counter current in the trickle bed. The effect of preparing condition on the activity of catalyst is discussed. The results show that the excellent catalyst is obtained by reduced at the temperature of 200 ℃ over 8 hours. Hydrophobic catalyst is high activity and stability as the amount of platinum content is 3%, the platinum can reach the economic use with the content of (1～2)%.