Abstract: The effects of 137 Cs irradiation (0 to 2 kGy) and MAP combination treatment on the survival and growth of Salmonella Spp are studied in sterile pork in the absense of competing microflora. A central composite response surface design is used to test the response of the pathogen to the treatments in a single experiment. Predictive equations are developed from the analyses of variances of the resulting data. The results show that the survival of Salmonella is singnificant decrease with the increase of irradiaiton dose, but there are no evident effects on the survival of salmonella due to the MAP. Five kinds of MAP don't show the difference on the growth of Salmonella. 50%CO 2 treatment showes the irradiation protection of Salmonella compared with air. The resullts indicate that the treatment combined irradiaiton with MAP is not more effective for controlling the survival and growth of Salmonella Spp.