Abstract: PROGRESS IN DEVELOPMENT OF DIAMINODITHIOL COMPLEXES AS BRAIN IMAGING AGENTYan Junhua Li Deyou Chen Lanfu(institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850)ABSTRACTThe situation of development of N2S2(diaminodithiol)complexes as brain imaging agent since the 1980s is briefly introduced. The structureeffect relationship, stereoisomers and biodistribution are discussed. The advantages of N2S2 complexes and as a potential brain imaging agent are described.Key words 99Tcm labeling brain imaging agents diaminodithiol complexes development