Abstract: THE PREPARATION AND QUALITY CONTROL OF 13NAMMONIA Wang Mingfang Sun Qiyin Zhao Jun Li Jiamin Wang Changqing Sun Aijun Song Shuqiang Wang Bing (PET Research Center, Zibo Wanjie Hospital, Shandong 255202) ABSTRACT13Npositron emission nuclide is produced by 16O（p,α)13N reaction in a small volume 16OH2O target. The target solution is irradiated with 16.5 MeV beam of protons for 5-20 minutes and then reduced to 13Nammonia using Devarda, s Alloy. The activity of 13Nammonia is 1.9-6.7 GBq, the radiochemical purity is more than 95% by HPLC, the concentration of carriedammonia is less than 1 mmol/L, the specific activity is 4.4 PBq/mol.Key words 16OH2O target Devarda, s Alloy reduction 13Nammonia preparation quality control