精神分裂症患者在氯丙嗪和氯氮平治疗中用放免法测定血清催乳素含量的意义

  • 摘要: 对32名男性精神分裂症住院患者,在用药前和用药后第4周、第8周分别用放免法测定血清催乳素(PRL)含量。结果表明,精神分裂症患者用药前血清PRL含量较对照组高。氯丙嗪治疗组用药后比用药前PRL含量明显增高,而氯氮平治疗组治疗期PRL含量无明显的变化

     

    Abstract: THESIGNIFICANCEOFSERUMCONCENTRATIONOFPRLDETERMINATIONINSCHIZOPHRENIACASESLiZhigangLiYuzhenWangHongzhiCuiGuofu(DaqingFifthHospital,163711)(DaqingThirdHospital,163712)ABSTRACTTheserumconcentrationofPRLisdeterminedbyradioimmunoassayon32patientswithschizophreniabeforeand4or8weeksaftertreatment.Theresultsshowthattheserumcon-centrationofPRLinpatientswhohavewithschizophreniaishigherthannormalcontrol.TheserumconcentrationofPRLinpatientswhohavereceivedchlorpromazinetherapyissig-nificantlyhigherthanthosewhohavereceivedchlozepinetherapy.Keywordsschizophreniaprolactin(PRL)chlorpromazinechlozepine

     

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