Abstract:
REGULARCHANGESOFLIPOPHILIC99Tcm┐ECDINBLOODJiaShaoweiGuoYilingLiangGuirong(ShenzhenPeople,sHospital,518020)ABSTRACTTheradioactivityconcentrationincreasesquicklyfolowingtheinjectionof99Tcm-ECDintovenousas“bolus”,reachingapeakin1min.Thewholebloodlipophilicfraction(Nw)ap-prochesmaximumin0.5minafterinjection,andthenreducesquicklywiththelapseoftime.Thevalueis0.76±0.06in1min.ThewholebloodlipophilicconstantWb(t)is0.81±0.03.NwandtheproductofWb(t)andtheradiochemicalpurityRpshowahighlysignificantcorre-lation(r=0.999,P<0.001).Keywordscerebralbloodflowlipophilic99Tcm-ECDSPECT