~(13)C-尿素呼气试验中~(13)C本底的初步探讨

  • 摘要: 在对北京、山东、江苏、贵州四个地区共495例正常受试者进行13C-尿素呼气试验诊断胃部幽门螺杆菌(HP)感染时发现,在不同地区人群呼气中13C本底值的波动很小(0.2%),在同一地区人群呼气中13C本底值的波动更小(≈0.1%)。每个人分别用相应地区本底均值及实测本底值进行HP感染的计算,诊断符合率在98%以上。以地区本底均值代替实测本底值可以降低成本,减轻工作量,为今后大规模开展HP感染的临床诊断和流行病学调查提供方便。

     

    Abstract: A PRELIMINARY INVESTIGATION OF ~(13)C BACKGROUND IN ~(13)C-UREA BREATH TESTHu Yufang; Li Xiaoming; Jiang Ji; Yue Xiangping; Wang Shizhen(Peking Union Medical College Hosptal, Beijing)Abstract:During the 13C-urea breath test which is used for diagnosis of the helicobacter pyloric infection(HP), the 13C background values are measured in 495 normal donors in Beijing, Shandong, Jiangyuand Guizhou. The fluctuation is less than 0. 2% for these areas and is about 0. 1% within the samearea. Through replacing of the individual 13C background values by the averaged values from localareas, the coincident rate for diagnosis of HP is higher than 98%.Keywords: 13C-urea breath test background

     

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