肺癌患者血清和肺组织中AIF及Ferr含量的测定

  • 摘要: 用放射免疫分析法(RIA)检测16例肺结核、24例肺炎、34例肺癌患者的血清酸性异铁蛋白(AIF)、铁蛋白(Ferr)含量,其值分别为142.2±84.5μg/l、104.2±59.3mg/l;148.8±79.5μg/l、107.3±46.8mg/l;260.7±126.3μg/l、161.5±75.3mg/l。肺癌组AIF、Ferr含量均显著高于对照组(P<0.01),较肺结核组和肺炎组也有显著增高(P<0.01)。因此,推荐血清AIF、Ferr含量作为肺癌特异性诊断的两个血清学指标。

     

    Abstract: DETERMINATION OF ACIDIC ISOFERRITIN AND FERRITIN IN THE SERUM AND CANCER TISSUES OF LUNG CANCER PATIENTSJiang Haiyan; Zhang Wanzhong(Nuclear Medicine Department,The Second Hosptial of Chongqing University of Meclical Sciences, 630010)Abstract:The serum AIF(acidic isoferritin) and Ferr(ferritin) levels are determined for 16 patientg withpulmonary tuberculosis, 24 patinets with pneumonia, 34 patients with lung cancer and 95 normaldonors with RIA method. The rogulng are 142.2±84. 5μg/l & 104. 2±59. 3 mg/l, 148. 8±79. 5μg/l & 107. 3±46. 8 mg/l, 260. 7±126. 3μg/l & 161. 5±75. 3 mg/l, and 103. 8±54. 3μg/l &72. 1±39. 5 mg/l, resepectively. The lung cancer patients group has a remarkably high level as compared with other groups(p<0. 01), waich indicates that the serum AIF & Ferr contents can be usedas important indices in lung cancer diagnosis.Keywords: acidic isoferritin ferritin lung cancer radioimmunoassay

     

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