多项肿瘤标志物对肺癌的诊断价值

  • 摘要: 采用放射免疫测定法对60例肺癌患者、60例良性肺部疾患患者进行β2-微球蛋白(β2-MG)、血清分泌型IgA(SIgA)、铁蛋白(SF)和癌胚抗原(CEA)含量的血清学联合检测。结果显示:肺癌组此四项血清肿瘤标志物均高于良性肺部疾患组及对照组,其阳性率分别为66.7%、70.0%、53.5%和60.0%,而60例肺癌组中无一例出现四项检测均阴性者。因此,β2-MG、SIgA、SF和CEA含量的测定均可作为诊断肺癌的辅助指标,且不同肿瘤标志物联合检测可明显提高肺癌检出率。

     

    Abstract: THEDIAGNOSTICVALUEOFSOMETUMORMARKERSONCARCINOMAOFLUNGSunBaoqingChenShuncunZhongNanshan(GuangzhouInstituteofRespiratoryDiseases,510120)ABSTRACTTheradioimmunoasaybyserologicaldetectionsincludedβ2-MG,SIgA,SFandCEAon60caseswithlungcancerand60caseswithbenigndiseasesoflungisdescribed.Theresultsshowthatthecontentsofthisfourtumormarkersinthegroupoflungcancerarehigherthantheonesinthegroupofbenigndiseasesoflung,aswelasthegroupofhealthcontrol.Theirpositivereactionratesare66.7%,70.0%,53.5%,and60.0%respectively,anditisspectacularthatnoonecaseamongthegroupof60caseswithlungcancerforthefoursero-logicaldetectionsisnegative.Therefore,notonlythelevelofβ2-MG,SIgA,SFandCEAcanbeusedasthesubsidiaryindicesoflungcancerdiagnosis,butalsothecombineddetec-tionoftumormarkerscanimprovethedetectingrateoftumors.Keywordscarcinomaoflungmarkersoftumorcombineddetection

     

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