Abstract:
THEAPPLICATIONOFα1┐MGRADIOIMMUNOASSAYINTHEDIAGNOSISOFKIDNEYDISEASESLiuGuifenWangJianchunZhangQingfengLiuShuyingHanWensheng(CangzhouCentralHospital,061001)LiZhihong(CangzhouHealthSchool,061001)ABSTRACTAnewmethodforthediagnosesofkidneydiseaseswithα1-microglobulin(α1-MG)ra-dioimmunoasayisdeveloped.276healthypersonsserumandurinearedeterminedbyα1-MGradioimmunoassay.Theresultshowsthattheserumnormalnumberis54.22±22.02mg/landtheurine5.57±2.63mg/l.Incontrast,thecounterpartsof358patientswithdif-ferentdiseasesarealsoexamined.Theresultshowsthatthereisaremarkablediferencebe-tweenurineα1-MGcontentofpatientssuferingfromsuchdiseasesasgestationhyperten-sion,renalinsuficiency,nephritisandthatofthehealthygroup(P<0.001).Themethodprovidesastable,sensitiveindexforthediagnosesofkidneydiseasesandtheexaminationofkidneyfunction.Itcanbewidelyusedintheclinicaldiagnosis.Keywordsα1-microglobulinradioimmunoassaykidneyfunctionkidneydiseases