Abstract: EVALUATION OF SERUM THYROGLOBULIN AND ~(131)ⅠWHOLE BODY SCANNING FOR THE DIAGNOSIS OF LOCAL RECURRENCE AND METASTASIS IN PATIENTS WITH THYROID CANCER AFTER OPERATION Shen Jiangfan；Gao Kejia（The Central Hospital of putuo District,Shanghai 200062）（The Sixth hospital,Shanghai 200233） ABSTRACT Serum thyroglobulin measured by RlA method and ~(131)Ⅰwhole body scanning are performed in 83differentiated thyroid cancer patients postoperatively． The seanning of 23 cases show that the metasta-sis of cancer is taken place，Among them，the serum Tg levels is higher than normal．The Tg levels be-fore stopping T_4 administration and after two weeks of stopping T_4 administration are compared for the20 patients. In addition， the follow-up studies with Tg are performed in five years for 10 cases. Theresults show that serum Tg is a sensitive and valuable in assessment of local recurrence or distant metas-tasis，the combination of sertim Tg and scanning is superior to eithcr procedure alone. key words thyroglobulin differentiate thyroid ~(131)Ⅰ whole body scanning