~(99)Tc~m右旋糖酐中~(99)Tc~mO_2胶体测定方法的探讨

  • 摘要: 通过纸层析、薄板层析和电泳方法的对照试验,小结了以醋酸纤维薄膜为支持物,以pH5.8磷酸缓冲液为介质的电泳方法及其电泳条件。该法能将放化杂质 ̄(99)Tc ̄mO_2胶体与 ̄(99)Tc ̄m右旋糖酐( ̄(99)Tc ̄m-Dx)分离、并测定其含量。

     

    Abstract: STUDY ON ~(99)Tc~m-COLLOID DETERMINQTION IN ~(99)Tc~m-DEXTRANHuang Tiansen(Shanghai institute for Drug Control,200233))ABSTRACT The comparative tests with paper chromatography,thin-layer chromatography and electrophoreticmethods are performed. The result indicates that the~(99)Tc~m-colloid can be separated from~(99)Tc~m-Dx.and the contents of~(99)Tc~mO_2 can be determined by the electrophoretic method which use cellulose acetateas the supports and 5. 8 pH phosphate buffer as the medium.Key words radiochemical purity~(99)Tc~m-dextran lymphoscintigraphic agent

     

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