甲状腺疾病患者血清EGF的测定及分析

  • 摘要: 应用放射免疫法对87例甲状腺疾病患者血清进行表皮生长因子(EGF)的测定,并与正常对照进行了比较。结果表明:38例甲亢患者血清EGF明显低于正常(P<0.01),其余甲状腺疾病患者血清EGF明显高于正常(P<0.05),同时,在甲亢和甲低组中EGF与T_3、T_4含量呈显著的负相关(P<0.01),而在甲状腺肿及甲状腺炎组中EGF与T_3、T_4含量的相关性无显著意义。提示进行血清EGF测定对进一步了解甲状腺疾病时甲状腺激素的分泌调节具有重要意义。

     

    Abstract: THE RADIOIMMUNOASSAY AND ANALYSIS FOR THE SEKUM EGF OFTHYROPATHY PATIENTSYin Shihua(Shengli Hospital of Dongying City,Shangdong Province,257055)ABSTRACT The serum EGF of 87 thyropes are analysed by radioimmunoassay and compared with health sub-jects.The results show that the serum EGF contents of 38 cases with hyperthyroidism are significantlyless than the normal(P<0.01),the serum EGF contents of the other sorts of thyropathy are signif-cantlv more than the normal(P< 0.05).Meanwhile, the contents bf EGF are significantly negativecorrelation with that of T_3 and T_4 in the hyperthyroidism and hypothyrodism groups.However,thecontents of EGF are not significantly correlation with that of T_3 and T_4 in the goiter and thyroditisgroups.It is noted that the analysis of EGF can be available to recognize the adjustion of thyroid hor-moes secretion in thyropathy.Key words thyropathy epidermal growth factor determining

     

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