Abstract: PREPAKARTION OF ω-~(125)I-PHENYL PENTADECANOIC ACIDCheng Guang；Zhao Jiandong（Shanghai Institute of Nuclear Research ，Academia Sinica, Shanghai 201800）ABSTRACT ω-~(125)I-phenyl pentadecanoic acid（IPPA） is a effective radiopharmaceutical for myocardial scintig-raphy and attractive labelled in recent years．The important feature of a I- 125 labelled phenyl groupin the terminal position of a fatty acid is the release of -(125)I-benzoic acid which stems from the finalβ-oxidation step of fatty acid catabolism. IPPA has been synthesized and labelled by the exchange of nu-clei with fast and simple labelling.Key words ω-~(125)I-phenyl pentadecanoic（IPPA）myocardial scintigraphy p-~(125)I－benzoic acid β-oxidation