Abstract: EVALUATION OF THYROGLOBULIN ASSAYYROGLOBULIN ASSAY IN THE FOLLOW-UP OF PATIENTS WITH DIFFERENTIATED THYROID CARCINOMALuo Jia；Li Jianguo；Ni Jichang；Ren Bangming； Chen Xianyu（Nuclear Medicine Department of First Affukuated Hospital Chongqing Medical University,630042）ABSTRACT Serum thyroglobulin level are measured in 38 patients who had undergone thyroidectomy and~(131)I ablation for differentiated thyroid carcinoma. Of 32 patients with metastases and recurrences，HTg lev-el are elevated（＞11μg／l）in 24（75％）and there are abnormal~(131)I imaging in l9（60％）．Of the re-maining patients with absence of thyroid cancer demonstrated by other clinical critera,HTg level are below 11 μg／l．These results suggest that the serum HTg level are of considerable value but position in the use of HTg levels is not as a replacement for~(131)I imaging in monitoring the activity of thyroid can-cer．Based on the study，however，the two methods can complement each other to achieve maximun sensitivity and reliblity.Key words HTg differentiated thyroid cancer~(131)I imaging