人总体水的GC/MS法测定

  • 摘要: 采用自化学电离GC/MS技术,以氘水为人体内示踪剂(0.6g/kg体重),测定了氘水在5例成人体内的平衡速度,并比较了在血、尿和唾液样品中的异同。根据摄入氘水后2.5、3.0、3.5小时唾液中同位素的平均稀释程度计算了一组正常中国成人体内总体水(TBW)等参数。

     

    Abstract: THE MEASUREMENT OF TOTAL BODY WATER(TBW)BY GC/MSJiang Ji;Jiao Ying;Li Xiaoming;Hu Yufang;Yang Zeyi;Wang Shizhen(Department of Nuclear Medical College Hospital,Beijing 100730)(Nationd Research Institute of Sports Medicine,Beijing 100029)ABSTRACT Equlibrium speeds of D_2O administered orally in 5 normal adults were measured with the technique of self-chemical ionization on GC/MS.The variations of D_2O in serum,urine and saliva werecompared too.The total body water(TBW)in 6 normal Chinese adults were determined according tothe average dilution in the saliva at 2.5,3 and 3.5 hours after D_2O intake at the dosage of 0.6g/kgbody weight.Key words total body water D_2O GC/MS

     

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