Abstract:
MEDICAL DIAGNOSIS OF RADIOIMMUNOASSAY FOR THE THP IN BLOOD AND UNINE zhu Guila Xu Sumei Chen Linna(Department of Nuclear Medicine,The Affiliated Hospital of Zhen jiang Medical Couege,212001)ABSTRACT The Tamm-Horsfall protein(THP)in bloob and urine of 10 1 healthy subjects and29 8 cases ofpatients with 8 different kinds of diseases are de tected by RIA kit.The average values of THP inheaIthy subjets' bIood and urine are l 59.89±51.57 ng/ml and 28.84±14.99 mg/24 h respective-ly,It is the same as detected by other authors. The resuIts show that the level of urine THP of Pa-tients ,including chronic renal failure,interstitiaI nephritis,chronic nephritis,lupus nephritis,diabet-ic nephritis and urinary infections,are much lower than that of heaIthy subjects(P<0.001),but thelevel of blood THP,are only lower in 4 kinds diseases,e.g.chronic renal failure,interstitial nephri-tis,chronic nephritis and lupus nephritls.In addition,theβ_2-MG in blood and urine,albumin in urineand BUN,Cr in blood in 27 8 cases are detected.It is found that the total abnormal rate of the bloodand urine THP is quite lower than that of urine albumin and β_2-MG,but higher than blood BUN andCr.Key words kidney disease radioimmunoassay tamm-horsfall protein