Abstract:
THE EVALUATION OF THYROTROPIN IMMUNORADIOMETRIC ASSAY KIT(MAGNETIC SEPARATION)IN CLINICAL APPLICATION Fu Benqi Chen Mingxi Tang Zhenlin(Department of Nuclear medieine, Sichaum promicial people' s Hospital,Chengdu 610072)ABSTRACT The average recovery of the thyrotropin immunoradiometric assay(TSH IRMA ) iS(104.8±4.1)%. The coefficients of variation in intra- and interassay are 9.0%and l 5.4%, respectively.The average batch coefficient of variation is 0.0077─0.02l 6.The 95%confidence interval of serumTSH IRMA was 0.41─4.28 mIU/l in 4 5 bIood donors.The levels of TSH in l l 3 cases with hyper-thyoidism are below 0.41mIU/l in IRMA,but normal inRIA.The lecels of TSH IRMA in57 caseswith hypothyroidism are higher than normal, and have more significant positive correlation with thatof TSH RIA(r=0.9566,P<0.01).The resuIts show that the TSH IRMA with magnetic separationis a sensitive method for thyroid function test.Key words thyrotropin immunoradiometric assay magnetic separation