TSHIRMA(M)药盒临床应用评价

  • 摘要: TSHIRMA(M)平均回收率为104.8±4.1%;批内和批间CV分别为9.0%和15.4%;ABCV为0.0077─0.0216。45例献血员TSHIRMA测定值95%可信限为0.41一4.28mIU/1,l13例甲亢TSHIRMA测定值均低于0.41mlU/l,而RIA值正常。57例甲低TSHIRMA值均高于正常,与RIA值呈高度正相关(r=0.9566,P<0.01)。结果表明,TSHIRMA(M)是检测甲状腺功能的灵敏方法。

     

    Abstract: THE EVALUATION OF THYROTROPIN IMMUNORADIOMETRIC ASSAY KIT(MAGNETIC SEPARATION)IN CLINICAL APPLICATION Fu Benqi Chen Mingxi Tang Zhenlin(Department of Nuclear medieine, Sichaum promicial people' s Hospital,Chengdu 610072)ABSTRACT The average recovery of the thyrotropin immunoradiometric assay(TSH IRMA ) iS(104.8±4.1)%. The coefficients of variation in intra- and interassay are 9.0%and l 5.4%, respectively.The average batch coefficient of variation is 0.0077─0.02l 6.The 95%confidence interval of serumTSH IRMA was 0.41─4.28 mIU/l in 4 5 bIood donors.The levels of TSH in l l 3 cases with hyper-thyoidism are below 0.41mIU/l in IRMA,but normal inRIA.The lecels of TSH IRMA in57 caseswith hypothyroidism are higher than normal, and have more significant positive correlation with thatof TSH RIA(r=0.9566,P<0.01).The resuIts show that the TSH IRMA with magnetic separationis a sensitive method for thyroid function test.Key words thyrotropin immunoradiometric assay magnetic separation

     

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