CEA、SF、β_2-MG、AFP、CG RIA联合检测对恶性肿瘤的诊断价值

COMBINED RIA OF CEA, SF, β_2-MG, AFP AND CG IN THE DIAGNOSIS OF MALIGNANT TUMOUR

摘要: 对1014例恶性肿瘤患者的血清CEA等五项RIA联检结果进行分析。其中:CEA以贲门腺癌、直肠腺癌、胃腺癌、结肠腺癌和肺腺癌阳性率较高,分别为58.3％、57.6％、55.8％、53.4％和58.6％;SF以原发性肝癌、恶性淋巴瘤、肺鳞癌和食管鳞癌阳性率较高,分别为57.1％、52.1％、53.9％和35.5％。β_2-MG各病例组的阳性率为40％—70％,AFP原发性肝癌组阳性率高达81.7％,CG原发性肝癌组阳性率也高达75.3％。RIA联合检测可互补不足,提供更多的诊断信息。

Abstract: Multiple tumour markers including serum CEA, SF, β_2-MG, AFP and CG are detected by RIA in 101 4 patients with malignant tumout. The results show that the positive rate of CEA in diagnosis of cardiac, rectal, gastric, colonic and adenocarcinoma are rather high, they are 58. 3%/, 57.6%, 55.8%,53. 4% and 58.6%; the SF has rather positive rate in primary hepatic cancer, malignant lymphoma, lung squamous cell cancer and esophageal cancer, they are 57.1%, 52. 1%, 53.9% and 35.5%. The positive rates of β_2-MG are 40%—70% for different malignant tumour groups. AFP and CG are very high mainly in primary hepatic cancer; their positive percentage are 81.7% and 75.3%. The combined RIA of multiple tumour markers would suppliment the deficiency of single marker detection and provided us with more diagnosis information.