免疫放射纸片法测儿童耳血TSH值评估碘缺乏病的探讨

SCHOOL CHILDREN TSH IRMA ON EAR BLOOD SPOT IN EVALUATION OF IDD

  • 摘要: 用免疫放射分析(IRMA)纸片法测定碘缺乏病区9—14岁小学生耳血TSH值,其几何平均值明显高于非病区,和小学生体内碘水平(尿碘)与甲状腺肿大率呈对应关系,和血清放射免疫测定结果类似,故建议列为评估碘缺乏病的常规方法。

     

    Abstract: Using immunoradiometricassay(IRMA) on blood spot, TSH Ievels were determined of ear blood of children aged 9—14 years in both iodine deficiency and non-deficiency areas. The results of 2.87±0.36 mIU/1(G±SD)and 0.48±0.76 mIU/1(G±SD) were obtained, respectively. And, interestingly, the finding was in quite correspondence with goitre rates of 37.1% and 5.3% as well as children urine iodine excretion of 34.5 μg/1 and 64.4 μg/1. All these data highly suggest that TSH IRMA on ear blood spot of children could be simple, easy adoptable and reliable in terms of its use in IDD monitoring and evaluation.

     

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