肺结核患者服药前后血清甘胆酸放免测定的临床意义

THE MEANING OF DETERMINING SERUM CG BY RIA BEFORE AND AFTER THE PULMONARY TUBERCULOSIS PATIENTS TAKE ANTITUBERCULOTION

摘要: 用放射免疫分析法(RIA)和全自动生化分析仪对128例肺结核患者服药前后血清甘胆酸(CG)、丙氨酸转氨酶(ALT)、天门冬氨酸转氨酶(AST)和γ-谷氨酰转肽酶(GGT)的变化进行了测定。结果提示服药后CG、ALT、AST、GGT较正常对照或服药前显著升高,其中CG的升高较其他指标早、幅度大。故血清CG可作为监测抗结核药物治疗中对肝脏损害的一项较可靠的灵敏指标。

Abstract: The serum CG, ALT, AST and GGT of 128 patients of pulmonary tuberculosis are determined by RIA and chemistry system before and after the patients took antituberculotic. The result indicates that after the patients take antituberculotic, the levels of Serum CG, ALT AST and GGT are higher than that of normal people. The level of serum CG rises earlier and higher than the other indexes. The level of serum CG may be a reliable and sensitive index which monitors the hepatotoxic during the antituberculotic treatment.