Abstract: The anisotropic coefficients of cylindric ~(241)Am-Be neutron source, produced by French Radiochemical Centre, were determined.The neutron source contains about 200 GB_q ~(241)Am.The anisotropic coefficient is 1.045 in the radial direction of the source. In the top and bottom directions of the source, the values are 0.836 and 0.884 respectively. The accuracy of anisotropic coefficient mainly depends on the statistical error of the counting. By the neutron sensitivity of the detector and the known anisotropic coefficients, it is able to estimate the strength and angular strength of the neutron source to be measured.